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The Genetics of TS: Who It Affects and How it Occurs in Families D. Pauls, Ph.D., M. Conneally, Ph.D. Addresses TS and inheritance, conditions associated with TS, OCD, ADHD, and common questions about TS and genetics. Features a glossary of genetic terms. 2005 Revision. Also available as download--see item M-113DD

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The Genetics of TS: Who It Affects and How it Occurs in Families DOWNLOAD ADOBE ACROBAT "PDF" FILE : D. Pauls, Ph.D., M. Conneally, Ph.D. Addresses TS and inheritance, conditions associated with TS, OCD, ADHD, and common questions about TS and genetics. Features a glossary of genetic terms. 2005 Revision.

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TSA Medical Letter-combined 1996,1997,2000,2004 Publication of TSA's national Medical Advisory Board covering recent, significant findings from scientific articles. Comprehensively discusses the implications of current data and focuses on clinical and research issues of interest to physicians, researchers and families. Also available as download--see item M-114DD

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TSA Medical Letter - Combined 1996, 1997, 2000, 2004 DOWNLOAD ADOBE ACROBAT "PDF" FILE : Publication of TSA's national Medical Advisory Board covering recent, significant findings from scientific articles. Comprehensively discusses the implications of current data and focuses on clinical and research issues of interest to physicians, researchers and families.

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TSA Medical Letter-1996 Single letter: 1996 issue. Also available as download--see item M-114dDD

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TSA Medical Letter-1996 DOWNLOAD ADOBE ACROBAT "PDF" FILE : Single letter: 1996 issue.

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TSA Medical Letter-1997 Single letter: 1997 issue. Also available as download--see item M-114eDD

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TSA Medical Letter - 1997 DOWNLOAD ADOBE ACROBAT "PDF" FILE : Single letter: 1997 issue.

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TSA Medical Letter-2000 Single Letter: 2000 issue. Also available as download--see item M-114fDD

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TSA Medical Letter-2000 DOWNLOAD ADOBE ACROBAT "PDF" FILE : Single letter: 2000 issue.

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TSA Medical Letter - 2004 Single letter: 2004 issue. Also available as download--see item M-114gDD

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TSA Medical Letter - 2004 DOWNLOAD ADOBE ACROBAT "PDF" FILE : Single letter: 2004 issue.

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Executive Function Abilities in Autism and TS S. Ozonoff, et al. J Child Psychol, Psychiat, 1994. Executive function is a model used to understand information processing and was developed to better understand and pinpoint causes of a variety of learning problems. This article suggests a new framework for investigating the thinking process of neurodevelopmental disorders.

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A Complete Genome Screen in Sib Pairs...Tourette Syndrome Am. J. Hum. Genet. Tourette Syndrome Association International Consortium for Genetics. Authored by the TSA Genetic Consortium, this article outlines members' collective findings about TS genetics. Two chromosomal areas are shown to be suspect in causing TS.

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Phamacotherapy In Children and Adolescents with OCD M. Grados, MD, MSN, PhD, L. Scahill, MSN, M.A. Riddle, MD, Child and Adolescent Psychiatric Clinics of North America, 1999. An examination of general principles of psychopharmacologic treatment of OCD in children and adolescents. Describes,profiles currently approved medications, side effects and drug interactions.

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The Treatment of ADHD in TS: Double-Blind Placebo-Controlled Study w/Clonidine/Desipramine H.S. Singer, MD, et at. Pediatrics 1995. Determining the best medications for people with TS who also have attentional problems is complex. In a well controlled drug trial, the investigators assessed 37 subjects with both ADHD and TS to determine the efficacy of two medications and to ascertain whether tic severity was influenced by taking these medications.

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Symptoms of Obsessive-Compulsive Disorder J.F. Leckman, MD, et al. The American Jour. of Psychiatry, 1997. One of the largest systematic studies of the symptoms of OCD. Data from 300 patients; authors develop a multi-dimensional view of OCD, including obsessions and checking, symmetry and ordering, cleanliness, washing and hoarding, etc.

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The Assessment and Coordination of Treatment of Children and Adolescents with OCD R.A.King, MD. L. Scahill, MSN, PhD. Child and Adolescent Psychiatric Clinics of North America, July 1999. Thorough and discussion of OCD treatment of children and adolescents; complete approach to diagnosis, effects on families, other medical conditions, academic performance.

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A Holistic Approach to Attention Deficit Disorder T. Armstrong, Educational Leadership, 1996. Author advocates looking at the whole child, emphasizing what children with ADHD can accomplish; talents of many who have attentional problems; postulates that underarousal rather than deficit may be at the root of the disorder.

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TS: Developmental Psychopathology of a Model Neuropsychiatric Disorder of Children D. Cohen, MD, The Strecker Lecture Series, 1990. This award winning lecture provides an in-depth look at TS genetics and neurobiology. Author delves into the case histories of two TS families and illuminates the philosophical workings of the minds of some people with TS.

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Medications for the Treatment of TS and ADHD K. Rickler, MD. The prescription of stimulant drugs for people with tic disorders continues to be controversial. This brochure discusses the benefits and risks of prescribing stimulant medications as well as effective alternative drugs for attentional problems. Potential side effects and current medical opinion about tic symptom exacerbation and stimulant prescription are covered. Contains detailed charts of commonly prescribed TS medications, including dosages and possible side effects.

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A Guide to TS Medications John T. Walkup, MD. A paper to keep families and medical professionals informed about the complexities of prescribing medications for people with TS. Covered are the most commonly prescribed medications for tic management, obsessive traits and attentional difficulties. Dosage guidelines and common side effects of the medication are discussed. 2008 Revision.Also available as download--see item M-313DD

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A Guide to TS Medications DOWNLOAD ADOBE ACROBAT "PDF" FILE : John T. Walkup, MD. A paper to keep families and medical professionals informed about the complexities of prescribing medications for people with TS. Covered are the most commonly prescribed medications for tic management, obsessive traits and attentional difficulties. Dosage guidelines and common side effects of the medication are discussed. 2008 Revision.

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Tourette's Syndrome: A Model Neuropsychiatric Disorder T.M. Hyde, MD, et al. JAMA, 1995. Through their experience studying twins with TS, the authors make the case for TS being a medical model for the study of several other neurobiological disorders. Covered are the natural history of TS, the interactions between genetics and environment, and results from neurochemistry, neuropathology and neuroimaging studies. Treatment issues are discussed as well.

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Pharmacologic Treatment of Tic Disorders L. Scahill, MSN, PhD, et al. Child & Adol. Clinics of North America, 2000. Tic disorders can vary considerably. This paper provides definitions for the various types as well as suggestions for medication treatment for different tic disorders and ADHD.

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Menstrual Cycle-Related Fluctuations of Tics in Tourette Syndrome M. Schwabe, MD, MS and R.Konkol, MD, PhD. Pediatric Neurology, 1991. Discusses the effects of PMS and the menstrual cycle on tics related to Tourette Syndrome.

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TS Medications and Pregnancy C. M. Berlin, Jr., MD, J. L. Juncos, MD, R. D. Bruun, MD. The best advice for women with tic disorders who are on medication is to talk with their doctors before getting pregnant. This pamphlet provides information that may be helpful, and suggests guidelines which may offer both caution and reassurance. 2006 Ed. Also available as download--see item M-328DD\r\n

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TS Medications and Pregnancy DOWNLOAD ADOBE ACROBAT "PDF" FILE \r\nC. M. Berlin, Jr., MD, J. L. Juncos, MD, R. D. Bruun, MD. The best advice for women with tic disorders who are on medication is to talk with their doctors before getting pregnant. This pamphlet provides information that may be helpful, and suggests guidelines which may offer both caution and reassurance. 2006 Ed.\r\n

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Invited Review, TS, Assoc.Conditions and the Complexities of Treatment M.M. Robertson, MD Brain, 2000. An outstanding overview, this article covers all aspects about what is known about the disorder. Includes data about epidemiology, genetics, pharmacology, and management of Tourette Syndrome. Emphasizes the complexities of the disorder, clinical manifestation, and associated conditions.

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Complementary and Alternative Medicine for Tourette Syndrome G. Erenberg, MD, C.M. Berlin, MD, K. Kompoliti, MD, S. Zinner, MD. Many people in the Tourette Syndrome community have wondered whether complementary and alternative treatments may be helpful. This discussion of what is known about Complementary and Alternative Medicine (CAM) is to help make informed decisions about alternative treatment approaches. 2006 Ed. Also available as download--see item M-333DD

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Complementary and Alternative Medicine for Tourette Syndrome DOWNLOAD ADOBE ACROBAT "PDF" FILE G. Erenberg, MD, C.M. Berlin, MD, K. Kompoliti, MD, S. Zinner, MD. Many people in the Tourette Syndrome community have wondered whether complementary and alternative treatments may be helpful. This discussion of what is known about Complementary and Alternative Medicine (CAM) is to help make informed decisions about alternative treatment approaches. 2006 Ed.

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Tourette Syndrome: A Neurobiological Disease That Can Mimic Allergy Drs. S. Roddy and R. Schwartz. Pediatric Asthma, Allergy and Immunology, 1988. Discusses the similarity between tics associated with TS and symptoms of allergy.

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Association of Allergy with Tourette's Syndrome Dr. Ho, et al. J Formos Med Assoc., 1999. Conducted in Taiwan, this investigation focused on clarifying the co-occurrence of TS and allergies. Researchers explored whether there is a connection for a clinic population in that country.

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Problem Behaviors & TS R. Bruun, MD, K. Rickler, MD, E. Kelman-Bravo, CSW, MS. Describes recent research and what is now known about the relationship of a variety of behaviors and TS. Contains helpful advice about the management of these problem behaviors for families and individuals with TS. Also available as download--see item M-337DD

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Problem Behaviors and TS DOWNLOAD ADOBE ACROBAT "PDF" FILE : R. Bruun, MD, K. Rickler, MD, E. Kelman-Bravo, CSW, MS. Describes recent research and what is now known about the relationship of a variety of behaviors and TS. Contains helpful advice about the management of these problem behaviors for families and individuals with TS.

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Development of Behavioral and Emotional Problems in TS H. Singer, MD, et al. Pediatric Neurology, 1989. Using the Child Behavior Checklist, 78 male children were assessed for a variety of behavioral problems. The relation to tic severity covered.

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Peer Problems in Tourette's Disorder A. Stokes, MD, et al. Pediatrics, 1991. Detailed research findings of peer problems in children with TS. Includes statistical results obtained from these studies.

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Dentistry and Tourette Syndrome: a Guide for Patients & Dentists Your dentist wants to know about your TS! Here is a discussion about a range of issues that concern dentistry and TS. by C. B. Korman. Also available as download--see item M-352DD

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Dentistry and Tourette Syndrome: a Guide for Patients & Dentists DOWNLOAD ADOBE ACROBAT "PDF" FILE : Your dentist wants to know about your TS! Here is a discussion about a range of issues that concern dentistry and TS. by C. B. Korman.

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Tourette Disorder S.H. Zinner, MD Pediatrics in Review, 2000. Thorough and detailed overview article covering all aspects of TS treatment. Complex diagnoses, comorbidity, common medications and dosages are but a few of the topics covered.

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An Epidemiologic Study of Gilles de la Tourette's Syndrome in Israel A. Apter, MD, et al. Arh. Gen. Psychiatry, 1993. How many people have TS is a commonly asked question. This comprehensive study represents the largest random population ever assessed for the occurrence of TS. Over 18,000 male and female recruits to the Israel Defense Force were screened for tics and obsessive compulsive symptoms. The ratio between genders was assessed.

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Tourette Syndrome and Repeated Anger Generated Episodes C. Budman, MD & R. Bruun, MD. The phenomenon of uncontrollable anger described in this booklet occurs in a few people with TS. Rage is a poorly understood behavior that may or may not be associated with the neurologically-based root causes of TS. behavior that may or may not be associated with the neurologically-based root causes of TS. This brochure examines this behavior. Most importantly, it describes specifics to identify it, and considers whether there is an association with several other neurobiological conditions. Also available as download--see item M-357DD

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Tourette Syndrome and Repeated Anger Generated Episodes DOWNLOAD ADOBE ACROBAT "PDF" FILE : C. Budman, MD & R. Bruun, MD. The phenomenon of uncontrollable anger describes in this booklet occurs in a few people with TS. Rage is a poorly understood behavior that may or may not be associated with the neurologically-based root causes of TS. This brochure examines this behavior. Most importantly, it describes specifics to identify it, and considers whether there is an association with several other neurobiological conditions.

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Botulinum Toxin in the Treatment of Tics C.H. Kwak, PA, P.A. Hanna, MD, J. Jankovic, MD. Arch Neurol, 2000. The first study with a sizeable number of participants that assesses the efficacy of botulinum toxin injections. This intervention is limited to those with severe symptoms who do not respond to traditional treatments.

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PANDAS? Or PAND? Or Both? Or Neither? E.L. Kaplan, MD. Contemporary Pediatrics, 2000. This brochure discusses the pieces of the "PANDAS" puzzle but notes that despite great interest among parents, pediatricians, and on the web, the PANDAS phenomenon is still poorly understood scientifically.

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Gilles de la Tourette Syndrome: Symptomatic Trt Based on Evidence Drs. M.M. Robertson & J.S. Stern. Euro Child & Adoles Psychiatry, 2000. A thorough discussion of a wide variety of TS symptomatology addressing causality, clinical characteristics, psychopathology and assocated behaviors. Summarizes the most recent researh findings in these and other areas. Focuses on the latest medical and other treatment approaches.

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